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Research interests and expertise: Chiara’s research is dedicated to the in silico design (docking, molecular dynamics) and advanced organic synthesis of small heterocyclic-based molecules, targeting oncological diseases and Malaria.

Background and education. Chiara obtained a Master’s Degree with honors in Medicinal Chemistry and Pharmaceutical Technology at the University of Torino, Department of Drug Science and Technology, in April 2020, with a Thesis focused on the application of a bioisosteric approach in the design of innovative inhibitors of Aldo-Keto Reductase 1C3 (AKR1C3) to target prostate cancer. In November 2021, she was awarded with the Silver Medal of the University of Torino for her Master’s career (academic year 2018/2019). In October 2020 she started a Ph.D. program in Pharmaceutical and Biomolecular Science, at the Department of Drug Science and Technology (University of Torino). Chiara finally defended her Doctoral Thesis titled “Inhibition of Enzymes Involved in the Induction of Apoptosis and Differentiation as well as Drug-Resistance in Myeloid Leukemias” (tutor Prof. Boschi) in May 2024, achieving her Ph.D. with honors.

Publications (Sep 2024, Scopus).
Publications in peer-reviewed journals: 3
Scopus citations: 15
Oral presentations: 1
Flash communications: 3
Posters: 9
Covers: 1
Scopus ID: 58180374300
ORCID: https://orcid.org/0000-0002-7726-3162

Visiting research activities.
·       Nov 2021 – Mar 2022 Mass Spectrometry Laboratory, Analytical Instrumentation Unity, at the Istituto di Ricerche Farmacologiche Mario Negri (Milano); Development of new methods for the detection of hDHODH inhibitors metabolites after microsomal incubation (tutor: Dr. Bagnati).
·       Mar 2022 – Jun 2022 Department of Synthesis and Chemical Technology of Pharmaceutical Substances, Faculty of Pharmacy, at the University of Lublin (Poland); Development of new dual inhibitors of AKR1C3 and CYP17A1 to target prostate cancer (tutor: prof Wròbel).
·       May 2023- Aug 2023 Department of Drug Design and Pharmacology of the University of Copenhagen; crystallization and x-ray structural analysis of complex of AKR1C3 enzyme and its inhibitors (tutor: Prof Mirza).
·       Sep 2023- Dec 2023 Department of Pharmacy of the University of Pisa ; molecular modeling studies (docking evaluation, molecular dynamics, and binding free energy determination) of novel hDHODH inhibitors (tutor: Prof Tuccinardi).

Teaching activities. Chiara covered the role of assistant to the teaching activities of different DSTF and Chemistry department courses. In particular:
·       June 2024 ·       “Path for Transversal Skills and Orientation (PTSO)” tutoring (40 h) - 1 high-school student from Liceo Classico Massimo D'Azeglio (Torino), activity title: “The process of drug development: from drug discovery to clinic"
·       2023-2024 “Laboratory Activities of Virtual Reality” (50 h) - Master’s degrees in Pharmacy and Medicinal Chemistry and Pharmaceutical Technology - UniTo.
·       2023-2024 “Methods of Synthesis and Pharmaceutical Development” - Master’s degree in Chemistry (4 h),
·       2023-2024 “Drug Analysis II- Module I” (8 h) - Master’s degree of Medicinal Chemistry and Pharmaceutical Technology - UniTo.
·       2023-2024 “Drug Synthesis” (8 h) - Master’s degree of Medicinal Chemistry and Pharmaceutical Technology - UniTo.
·       2023-2024 “Laboratory of Advanced Drug Synthesis” (8 h) - Master’s degree of Medicinal Chemistry and Pharmaceutical Technology - UniTo.
·       2022-2023 "Exercitation of Food Chemistry and Phytopharmacy" (20 h) - Bachelor’s degree program of Herbal Products - UniTo

Department roles.
·       Jan 2023 – to date Member of DSTF Public Engagement communication sub-commission (social media campaign of the Department).
·      Mar 2022-Mar 2024 Ph.D. students’ representative at DSTF.